Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. It should only be used in small amounts for short periods as a cream. A critical scoping review of external uses of comfrey (Symphytum spp.). Stickel F, Seitz HK. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. Eucalyptus oil is used externally to stimulate blood flow. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. After the consistency begins to thicken, turn the mixer up a little bit. View abstract. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. Comfrey contains toxic substances that cause liver damage, cancer, and death. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties Customer Reviews Ingredients Full ingredients Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). Generic name: comfrey [COM-free] Please read the Topical Use Safety section of this article (above) before using. Penetration of lycopsamine from a comfrey ointment through human epidermis. View abstract. Liver injury from herbal and dietary supplements. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Registered VAT no. The recipe makes about 6 small jars. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. You and your healthcare provider should weigh the pros and cons and use it only under their supervision. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Other herbal supplements that may have benefits for back pain include: Some other supplements that may be useful for osteoarthritis are: Back pain is often treated with medication such as over-the-counter pain relievers. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Verywell Health's content is for informational and educational purposes only. Turn off heat and give it a good stir. Simply massage into the skin as required. Koll R, Klingenburg S. [Therapeutic characteristance and tolerance of topical comfrey preparations. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. View abstract. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). J Pain. A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. The warm weather has a way of encouraging us to get outside and move our bodies more. Would you like to win our brilliant Botanical Business Package with nearly $1,000 in prizes? J Pharm.Belg. Mix for about 10 minutes, until nice and whipped. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Comfrey is considered likely unsafe to use if you are nursing a baby. It may contain small amounts of toxic pyrrolizidine alkaloids. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. To make this recipe, first, you must prepare the comfrey root tincture. View abstract. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. Centurian, South Africa: Medpharm Scientific Publishers. View abstract. Sometimes, massaging on topical ointments can help reduce pain and inflammation. For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! Taking comfrey along with a medication that can harm the liver might increase the risk of liver damage. Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . Comfrey is an herb in the Boraginaceae family and has small purple flowers. , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. Comfrey is a flowering shrub that grows in Europe, Asia and, now, North America. View abstract. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Read our. Avoid comfrey with certain medical conditions, such as liver disease. 12 drops peppermint (Mentha piperita) essential oil 2012;(1):41-42. Mackinnon, M. In general practice, 'always expect the unexpected'. Acupuncture has also shown solid evidence of benefit for back pain. It produces clusters of purple, blue, and white flowers, and it's famous for its long . Am J Med 1990;89:547-8. Pour into bowl /jug big enough for all ingredients and safe for the mixer. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. ). Comfrey can also contain echimidine, pyrrolizidine alkaloids (PAs), and symphytine, which can damage the liver, are carcinogenic (cancer-causing) and may harm a fetus. This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. The way that they work is by blocking small blood vessels in the liver. #HBTechCareers. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). A handbook for practice on a scientific basis. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. Using different formulations together increases the risk of an overdose. This item: Terry Naturally Traumaplant Comfrey Cream - 1.76 oz (50 g) - Non-Staining Topical Botanical, Free of Toxic Pyrrolizidine Alkaloids (PAs) & Parabens - for External Use Only $20.76 ($11.80/Ounce) Dr. Christopher's Comfrey Ointment, 2 Ounce $11.99 ($6.00/Ounce) Dr Christopher's Formula Complete Tissue and Bone Ointment, 4 Ounce Kucera, M., Kalal, J., and Polesna, Z. Although not all side effects are known, comfrey is thought to be possibly safe when applied to unbroken skin for less than 10 days. Our associates are qualified to advise, visit us online or in store for unparalleled advice. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. Symphytum officinale L., dermal use (Flexagile cream)]. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. 2011;10(3):147-56. In another study, participants with ankle sprains received either comfrey root extract cream or diclofenac gel, a nonsteroidal anti-inflammatory drug (NSAID). Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. 2021;83:e249209. Avoid taking comfrey orally (by mouth). The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). 2012;101(4):211-216. Therapeutic use of comfrey is limited because of its toxicity. Set aside cup for the cream recipe and store the rest in a glass jar. The participants were assigned three weeks of treatment with two grams of either comfrey ointment or a placebo three times a day. To Use. All rights reserved. (2013). (2004). Efficacy of a comfrey root (Symphyti offic. 2019;24(12):2272. doi:10.3390/molecules24122272, Staiger, Christine. Resuscitation 2008;76(3):323-324. Journal of chiropractic medicine, 10(3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003, Stam, C., Bonnet, M. S., & van Haselen, R. A. Using a supplement like comfrey may have potential side effects. . A symptomatic treatment of minor sprains and bruises. In a randomized multicenter study with 164 ankle sprain patients, swelling and pain were improved more successfully using a comfrey root extract compared to a diclofenac gel (Predel et al., 2005). Spine(Phila Pa 1976). Huxtable RJ, Awang DV. Call your doctor for medical advice about side effects. Comfrey cream contains several active components (substances). View abstract. Do not use extra comfrey to make up the missed dose. 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005, Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. View abstract. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. Br J Sports Med. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. cup organic sunflower oil BMJ Case Rep. 2016. Copyright Holland & Barrett Retail Limited, 2022. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Dosage: How Much Comfrey Cream Should I Use? Skip the missed dose if it is almost time for your next scheduled dose. As the consistency thickens some more, turn the mixer up a little bit more. Consult your healthcare provider before using. Megan Nunn, PharmD, is a community pharmacist in Tennessee with twelve years of experience in medication counseling and immunization. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Some people ingest comfrey roots or leaves or use them in teas. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. Rad. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Be sure to choose organic carrier oils and essential oils when possible. The efficacy and safety of comfrey. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Available for Android and iOS devices. Need some help with an order or want to speak to a member of our Customer Services team? Adv.Ther 2000;17(4):204-210. Topical comfrey is for use only on the skin. We comply with the HONcode standard for trustworthy health information. Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. How do you use it and are there any side effects? To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. NCCIH. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. 2017;83:1-4. If you're considering using the cream, consult your healthcare provider first. This site uses cookies to improve your experience. View abstract. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. (Grube et al., 2007). Stam, C., Bonnet, M. S., & van Haselen, R. A. Do not give any herbal/health supplement to a child without medical advice. International Journal of Pediatrics and Adolescent Medicine, (4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002. Cover, but leave a small air opening. Comfrey is a fast-growing plant whose leaves and roots have been used historically for wound healing and other conditions. Close LOGIN FOR DONATION. Do not use this product if you have a sensitivity to any of the ingredients. 2758955. Using it no more than four to six weeks a year as a general guideline would be best. Knit bone, Eucalyptus, Rapeseed Oil, BHA. Comfrey is avoided on cuts or puncture wounds for this reason. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). This is the tincture. Wound-healing effects of a symphytum herb extract cream (Symphytum uplandicum Nyman) in children: A randomized double-blind study. Whether youve been hiking, biking, playing, or enjoying water sports, comfrey cream can be a wonderful ally in supporting achy muscles that result from physical, summertime activities. MedlinePlus Medical Encyclopedia. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. The cream was applied to the local lumbar area 4x during the day of the exercise, with the first application being pre-exercise (Jurcau & Jurcau, 2013). For topical comfrey cream, look for products labeled as free of pyrrolizidine alkaloids. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Seal with a lid and then label with the ingredients and date. (10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001. Supplements marketed for body-building (ex.. Here's 10 things essential oils are great for. If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. Fortschr Med Orig 2002;120:1-9. Jurcu, R., & Jurcu, I. Hepatology. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. It contains chemicals that are poisonous. Additionally, use on a deep cut may encourage healing of the outer skin the preparation comes in direct contact with faster than the deeper tissue, leading to abscess. Instructions. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption.
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