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Sheng returned to the department last fall as professor of neuroscience, a position he also held from 2001-08; the years in . Broad Institute is committed to making the extensive data, methods, and technologies it generates rapidly and readily accessible to the scientific community to drive biomedical progress around the world . Morgan Sheng Email: Postdoc 1990-1994: Co-Director of Stanley Center for Psychiatric Research, MIT Broad Institute: Website: George Lopez Email: Graduate Student 1989-1995: Associate Professor, Rush University: Website: Dan Doherty . The Sheng lab uses interdisciplinary approaches to elucidate the mechanisms of humoral immune response to infection and to understand the role of B cells in autoimmunity. Faculty Assistant Mary Gidaro mgidaro@princeton.edu 105 Thomas Laboratory p 609-258-8956 f 609-258-1704. We seek to understand how lipid macromolecules are generated, stored, and metabolized, and how lipid processes function in membrane biology and cell physiology. To combat the COVID-19 pandemic, nonpharmaceutical interventions (NPI) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARI).Etiologically diagnostic data from 142 559 cases with ARIs, who were tested for eight . Is this useful? M Sheng, S Smiga, A Bulfone, . Job title Senior Technical Lead. Fei Chen, Principal Investigator. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad's Stanley Center for Psychiatric Research and as a professor of . Sheng completed his medical training and a residency in general medicine in London, UK. Morgans groundbreaking research has accelerated the understanding of brain synapses in health and disease, said Eric Lander. Broad Institute of MIT and Harvard As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to . msheng@mit.edu. Broad brings people together to advance the understanding and treatment of disease. Average $24.55 per hour. The MIT Department of Biology ("Course VII") is a center for research and teaching in the life sciences. We work closely with pharmaceutical, biotech, and technology partners to accelerate the translation of our discoveries. Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue, From: https://picower.mit.edu/morgan-sheng, A physician and a scientist, Morgan Sheng. BBD has a multidisciplinary technical portfolio that includes genomic measurements, synthetic biology, regenerative medicine and advanced therapies, biomaterials, diagnostics, and complex microbial . Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research. The research of her group focuses on translating emerging genetics into biology and to enable next-generation therapeutics to treat psychiatric illnesses. POSTED ON 12/18/2022 AVAILABLE BEFORE 5/17/2023. BBD has a multidisciplinary technical portfolio that includes genomic measurements, synthetic biology, regenerative medicine and advanced therapies, biomaterials, diagnostics . JR Lee, AW Dunah, M Sheng, E Kim. Prof. Gong's research group focuses on the design, synthesis/fabrication, and characterization of novel materials and devices. Our study identifies LSD1 as a potent inhibitor of anti-tumor immunity and responsiveness to immunotherapy and suggests LSD1 inhibition combined with PD- (L)1 blockade as a novel cancer treatment strategy. US 5849868 A The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. A physician and a scientist, Morgan Sheng is author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. Find out how to join the Broad as an employee or associate member. Institute Member, Broad Institute of MIT and Harvard Office: 46-3143A / Phone: (617) 715-4898 . This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. Email. Many of their ongoing projects are multidisciplinary, bridging engineering with materials science, chemistry, and life sciences. 617-714-7022. Senior investigator, Chief of Synaptic Functions Section, NINDS, NIH. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). This job is no longer available, but here are similar jobs you might like. Broad Genomics Platform sequences a whole human genome every four minutes. . USA. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. . A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation . She leads the ICE-T (ion channel electrophysiology and technology) effort enabled by Broadnext10 initiative to utilize state-of-art technologies for studying ion channels and electrogenic transporters, and to find novel ways to modulate these highly specialized membrane proteins. However, research on the predictive potential and clinical importance of mitophagy-related genes (MRGs) in hepatocellular carcinoma (HCC) is currently lacking. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad's Stanley Center for Psychiatric Research. +1 415 734-2717. The trainees in core faculty labs are typically engaged in one or more of the Broad programs, and often benefit from and collaborate with the Broad platforms. From 2008 to 2019, Sheng was Vice-President of Neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. The impact of Shengs research has been recognized by several prizes including the Fondation IPSEN Prize for Neuronal Plasticity and the Society for Neurosciences Young Investigator Award. San Diego under the guidance of Professor Sheng Zhong. is located in Taipei. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. Find our contact information, directions to our buildings, and directory. Featured publications are below. Published in NANO Letters, the study was led by Zhi Sheng and Deborah . Shawn.Sheng@nrel.gov 303-384-7106 . A past recipient of the Fondation Ipsen Prize in Neuronal Plasticity and the Young Investigator Award of the Society for Neuroscience. Important new look into the Alzheimer's brain from a collaboration including Morgan Sheng, a Picower Institute affiliate professor based at . In 1990, he earned his Ph.D. in molecular genetics from Harvard University and completed his postdoctoral fellowship at the University of California, San Francisco. Following postdoctoral research in the lab of Lily Jan at the University of . A multimodal molecular cell-type atlas of the MOp. In collaboration with labs at ADARC, we sequence viral antigen-specific B cell receptors (BCRs) to identify immune signatures of infections including . From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. Outstanding Achievement Award, Society of Chinese Bioscientists of American (SCBA) Neuroscience Division (2005). Cambridge, MA 02139-4307 |(617) 253-5748, For Emergencies|Accessibility|Adapting to COVID, A physician and a scientist, Morgan Sheng. is working in Medical laboratories activities. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research. Apply Now Job Salary Company Rating Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research Matt received a Ph.D. in Chemical Engineering from the University of Maryland in 2001. Chemical biology and therapeutics science, Genome regulation, cellular circuitry, and epigenomics, Merkin Institute for Transformative Technologies in Healthcare, Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Several pre-existing RSV lineages powered the 2022 surge, Blood stem cells are susceptible to ferroptosis, a type of cell death, Rare genetic variants can reveal much about disease biology, Researchers map brain cell changes in Alzheimers disease. These new phases exhibit huge unit cells (V . In a new study published in Oncogenesis, Zhi Sheng and Rob Gourdie of the Fralin Biomedical Research Institute at VTC describe how two protein-targeting drugs - when combined with chemotherapy - yield synergistic cytotoxicity to treatment-resistant glioblastoma. The Xpert HIV-1 qualitative assay (Xpert HIV-1 Qual; Cepheid, Sunnyvale, CA, USA) for early infant diagnosis is considered to be a point-of-care test according to the REASSURED criteria; 9 although it takes 90 min, the assay is able to provide results on the same day as testing. Learn about breakthroughs from Broad scientists. the broad institute of mit & harvard is looking for outstanding postdoctoral scholars to join the laboratory of morgan sheng, co-director of the stanley center for psychiatric research, the mission. Research. Popular Locations. We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap). Sheng received a B.A. He has served on the editorial boards of Neuron, Journal of Neuroscience, and Current Opinions in Neurobiology. 1 Broad Institute of MIT and . 1-6 The GI tract is crucial for inducing many T-cell-mediated inflammatory disorders, including graft-versus-host disease (GVHD) in individuals who receive . Jiaoti Huang, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave., 13-229 CHS . I am currently an Associate Computational Biologist II in the Morgan Sheng lab at the Broad Institute of MIT and Harvard. Sheng does research in Physical Chemistry, Solid-state Chemistry and Solid . Postdoctoral Associate - Sheng Lab Cambridge, MA $47K - $89K ( Glassdoor est.) 213: 2009: ARF6 and EFA6A regulate the development and maintenance of dendritic . (+1) 617-452-2588. The Elowitz lab is committed to creating an inclusive, diverse, and supportive environment, and we encourage postdoc applications from groups historically under-represented in science. Dr. Sheng lab haspublisheda number of important studies focused on axonal transport of mitochondria and endolysosomes in healthy and diseased neurons. 617-939 . For a full list visit the lab website linked above. We join with institutions and scientists the world over to address foundational challenges in science and health. All Companies Boston University (6) Brigham & Women's Hospital(BWH) (3) Northeastern University (2) Veeva (2) University of Massachusetts Medical School (2) Veeva Systems (2) Dana-Farber Cancer Institute (2) Berklee College of Music, Incorporated (1) The Broad Institute, Inc. (1) Mitsubishi Electric Research Laboratories (1) Suffolk University (1) Broad Institute (1) Boston Conservatory at . 617-714-7021. The Broad Institute of MIT and Harvard is looking for an exceptional candidate to join the Sheng lab or the Therapeutics group (led by Professor Morgan Sheng) in the Stanley Center for Psychiatric Research. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. Geplaatst op 3 juli 2022 door Feng Laboratory McGovern Institute For Brain Research 43 Vassar Street, Office: 46-3133 Cambridge, Massachusetts 02139 Phone: (617) 715-4920 Website: fenglaboratory.org. He was first trained as a molecular biologist in the University of Hong Kong Sean Moran is a neuropharmacologist with a strong passion for translational neuroscience research who earned his PhD from Vanderbilt University under the mentorship of P. Jeffrey Conn. During his Lei is an interdisciplinary scientist with skills in neuroscience, machine learning, and software development. Published by at July 3, 2022. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The . Some of their efforts include multifunctional drug/agent nanocarriers for the . I am excited to return to academia and establish a research lab at the Broad, said Sheng. Sheng started his academic career, centered on molecular and cellular neuroscience, in 1994 at Massachusetts General Hospital and Harvard Medical School, and later moved to MIT as the Menicon Professor of Neuroscience. Fusarium wilt of banana, especially Tropical Race 4 (TR4) is a major factor restricting banana production. Sheng Tai. We are currently located in this beautiful Life Science Research Building at the main campus. Check out this video for a look into our community! Eye and Ear Institute 915 Olentangy River Road Suite 4000 Columbus, OH 43212. . By creating this job alert, you agree to the LinkedIn User Agreement and Privacy Policy. About. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from The Scripps Research . DOI: 10.1115/1.4054996 Corpus ID: 250577941; Design and Control of SLPM Based Extensible Continuum Arm @article{Zhuang2022DesignAC, title={Design and Control of SLPM Based Extensible Continuum Arm}, author={Zheming Zhuang and Ze-Sheng Zhang and Yuntao Guan and Wei Wei and Mi Li and Zhao Tang and Rongjie Kang and Zhibin Song and Jian Sheng Dai}, journal={Journal of Mechanisms and Robotics . Lab studies the genetics underlying neural development to identify new diagnostic and therapeutic approaches for a broad range of disorders that compromise brain and organ system development. and sequencing, takes ~3 d to process up to 192 samples manually. Access free classroom materials and more for STEM educators, parents, students, tutors, and others. (1st class honors) from Oxford University and obtained his medical degree and training at London University. . Broad Genomics Platform sequences a whole human genome every four minutes. Postdoctoral Associate - Sheng Lab in The Broad Institute, Inc. Cambridge, MA. sheng.ding@gladstone.ucsf.edu. The successful candidate will join a multidisciplinary group and perform cutting-edge basic and/or translational research on the molecular, cellular and . The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Merkin Building Using genetic mouse models, his group is addressing several fundamental questions: (1) how mitochondrial transport is regulated to sense changes in synaptic activity, mitochondrial integrity, axon injury and pathological stress; (2) how neurons coordinate late endocytic transport and autophagy-lysosomal function to maintain cellular homeostasis and distal degradation capacity; (3) how impaired transport contributes to synaptic dysfunction and axonal pathology in neurodegenerative diseases. He will also return to MIT, after a decade in industry, as a professor of neuroscience in the Department of Brain and Cognitive Sciences, where he will be an affiliate of both the McGovern Institute for Brain Research and the Picower Institute for Learning and Memory. Copyright Pentagram. The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health. He joined NINDS as an investigator in 1997 and is now a tenured senior investigator . We work closely with pharmaceutical, biotech, and technology partners to accelerate the translation of our discoveries. The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. In Situ Biology Join Us Contact The Chen Lab. Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries. Find us on Twitter. Nathaniel earned his MA in psychology from Boston University in 2022 William Ned Martenis is a therapeutics group research associate affiliated with the Pan and Sheng labs, where he primarily develops, troubleshoots, and runs high-throughput assays designed to better Kate graduated from American University in 2016 with a BA in Psychology. Broad Institute 4.0. . Every summer, 18 high school students spend six weeks at Broad working side-by-side with mentors on cutting-edge research. Our group aims to redesign existing proteins and engineer new proteins that overcome these limitations. Featuring speakers from the Nedivi, Littleton, and Sur labs. Our community is deeply engaged in the local, national, and global effort to respond to COVID-19. Job functions Engineering, Information Technology, Operations. I am looking forward to joining this community of innovative researchers and applying my expertise to discover novel therapies and improve the lives of people with mental illness.. 2012 - 2017 Ershela Durresi, Ph.D. Medical Student, Harvard Medical School . Shawn has a broad range of experience: mechanical and electrical system modeling and analysis; data sensing and sensor placement; signal processing; machine learning and artificial intelligence; machine defect classification and level evaluation; machine life prognosis; multi scale modeling; traditional and . Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. Posted on July 4, 2022 by . Cambridge, MA 02139 As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to shape the centers scientific vision and direction, and oversee the centers efforts to develop therapeutics for schizophrenia and other serious mental illnesses. As the Director for Translational Neurobiology at Stanley Center, Dr. Pan aspires to translate the understanding of the genetics and biology of psychiatric and neurological illnesses to novel therapeutics for severe mental illnesses. Dejanovic B, Huntley MA, De Mazire A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M. Neuron. Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. 69, Lide St. Zhonghe Dist., New Taipei City, TW. Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward. Frequently searched careers. Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations. Broad brings people together to advance the understanding and treatment of disease. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental . You can contact the company at 02 2245 3355.You can find more information about at www.sl-lab.com.tw. Currently, the Sheng lab focuses on three areas of research: Immune response to infection and vaccination: We develop computational methods to study immune responses of humans and animal models. Morgan Sheng Core Institute Member, Broad Institute of MIT and Harvard Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute Professor of Neuroscience, Department of Brain and Cognitive Sciences Affiliate Member, The Picower Institute for Learning and Memory Affiliate Member, McGovern Institute for Brain Research The four magnified images on the right show how the cell takes up the treatment across a span of 30 seconds. Blainey Lab Golub Lab Hung Lab Lander Lab Liu Lab Regev Lab Schreiber Lab Sellers Lab Xavier Lab Zhang Lab Institute Member labs Eric Alm, MIT Paola Arlotta, Harvard Picower Professor of Biology and Neuroscience; Director, RIKEN-MIT Laboratory for Neural Circuit Genetics. By taking the advantage of next-generation sequencing technique, he uses bioinformatics approaches to investigate features of B cell repertoires, and to study mechanisms modulating the maturation process of broadly HIV-1 neutralizing antibody lineages in humans and animal models, with the aim of finding an optimal HIV . Structural Insights of Non-canonical U-U Pair and Hoogsteen Interaction Probed with Se Atom. yuansf@hku.hk. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. Dr. Sheng received his Ph.D. in Biochemistry from the University of Pennsylvania in 1993. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology at Massachusetts General Hospital and Harvard Medical School (1994-2001) before joining MIT (2001-2008). Gladstone-UCSF Institute of Genomic Immunology . Find out how to join the Broad as an employee or associate member. Email. SPANGLER LAB. The research of her group focuses on translating emerging genetics into biology and to enable next-generation . Cristea Lab Department of Molecular Biology 210 Thomas Laboratory Washington Road Princeton, NJ 08544 p 609-258-9425. sheng lab broad institute Yun-Sheng received his master's degrees in materials science and engineering from . Institute of Sustainability for Chemicals, Energy and Environment (ISCE 2) Institute of High Performance Computing (IHPC) . Sheng and coworkers made important discoveries regarding the molecular mechanisms of synapse weakening and loss, the contributions of microglia and innate immunity in neurodegenerative diseases, and the roles of genetic risk factors in the pathogenesis of Alzheimers disease, Parkinsons disease, ALS, and frontotemporal dementia. EEO is The Law - click here for more information, Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled. Isotianil is a monocarboxylic acid amide that has been used as a fungicide to control rice blast and could potentially induce systemic . yuansf@hku.hk. Category: research Scientists at Fralin Biomedical Research Institute develop new strategy for brain cancer treatment. This person will apply existing computational methods and interpret results within a biological context. By the end of 2022, Broads COVID-19 testing lab had processed more than 37 million tests. Browse 59 BOSTON, MA AUTISM RESEARCH job ($35K-$108K) listings hiring now from companies with openings. Lab Administrator. The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region. He has served on the editorial boards of Neuron, Journal of Neuroscience, and Current Opinions in Neurobiology. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. Lab website. Should have a demonstrated proficiency in R and/or Python, or related languages, Experience with and solid understanding of statistical analysis is required, Familiarity with next-generation sequence data analysis tools and packages, particularly those for bulk and single cell/nucleus RNA-seq, Understanding of molecular biology and next generation sequencing is highly preferred, Familiarity with working on a computing cluster/server (important skills: Unix/Linux, shell scripting). Shengs molecular studies of the structure and function of synapses (the communication junctions between brain cells) while at MGH and MIT have enhanced our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, neurodevelopmental disorders, and dementia. Lei received his PhD in Neuroscience under the doctoral program of "Molecular Physiology of the Brain" Nikita completed his Cognitive Science Bachelor's degree from McGill university in the spring of 2019 focusing in the fields of Neuroscience and Philosophy. Queen's University. Check out this video for a look into our community! Get email updates for new Research Scientist jobs in United States. We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders. Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, 518052 P. R. China Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, 999077 .